Late-neonatal SARS-CoV-2 infection: A curious case of COVID‑19 with respiratory co-infection and treatment with surfactant
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Abstract
At the height of the COVID‑19 pandemic, South Africa became the epicentre of the continent. Considering the paucity of data on
COVID‑19, we aimed to describe the clinical picture in a neonate, alert healthcare workers to the presence of co-infection with COVID‑19 and propose alternative treatment modalities. The use of surfactant was based on the pathophysiological mechanisms of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). There is mounting evidence in support of using surfactant in the management of severe COVID‑19. While viral co-infection is a common occurrence among neonates, our case shows that COVID‑19, together with rhinovirus infection, may result in a more rapid clinical deterioration, as opposed to rhinovirus infection in isolation.
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References
Sankaran D, Nakra N, Cheema R, Blumberg D, Lakshminrusimha S. Perinatal SARS‐CoV‐2 infection and neonatal COVID‐19: A 2021 update. Neoreviews 2021;22(5):e284‐295. https://doi.org/10.1542/neo.22‐5‐e1001
Di Nardo M, van Leeuwen G, Loreti A, et al. A literature review of 2019 novel coronavirus (SARS‐CoV2) infection in neonates and children. Pediatr Res 2021;89(5):1101‐1108. https://doi.org/10.1038/s41390‐020‐1065‐5
Liguoro I, Pilotto C, Bonanni M, et al. SARS‐CoV‐2 infection in children and newborns: A systematic review. Eur J Pediatr 2020;179:1029‐1046. https://doi. org/10.1007/s00431‐020‐03684‐7
Yonker LM, Shen K, Kinane TB. Lessons unfolding from pediatric cases of COVID‐19 disease caused by SARS‐CoV‐2 infection. Pediatr Pulmonol 2020;55(5):1085‐1086. https://doi.org/10.1002/ppul.24748
Dong Y, Mo X, Hu Y, et al. Epidemiology of COVID‐19 among children in China. Pediatrics 2020;145(6):1‐10. https://doi.org/10.1542/peds.2020‐0702
Afewerky HK. Pathology and pathogenicity of severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2). Exp Biol Med 2020;245(15):1299‐ 1307. https://doi.org/10.1177/1535370220942126