Long-term mental health and wellness of South African children treated for multisystem inflammatory syndrome in children: An observational study

Main Article Content

D R Abraham
N A Yunis
R H Glashoff
H Rabie
M M Van der Zalm
A Lachman

Abstract





Background. Data on mental health and wellness of children with multisystem inflammatory syndrome in children (MIS‐C) from Africa are limited.


Objective. To investigate the long‐term mental health and wellness outcomes in a South African cohort of children with MIS‐C.


Methods. This study reports on the long‐term mental health of 27 such patients using age‐appropriate developmental, clinical and neuropsychiatric validated scales, 6 ‐ 24 months after the initial diagnosis.


Results. Nineteen (70%) children did not meet any criteria for psychiatric disorders. Eight participants met the criteria for a pre‐MIS‐C‐ dated psychiatric diagnosis, based on the fifth edition of the Diagnostic and Statistical Manual of Mental disorders Three (11%) met the criteria for an anxiety disorder, three (11%) for adjustment disorder, one (4%) for attention deficit hyperactive disorder (ADHD) only, and one (4%) for both anxiety and ADHD.


Conclusion. None of the participants met the diagnostic criteria for psychotic illnesses, sleep issues, mood disturbances or posttraumatic stress disorder related to MIS‐C. The study enabled recognition and management of pre‐dated MIS‐C mental health risk and psychiatric diagnosis.





Article Details

Section

Short Reports

Author Biographies

D R Abraham, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa

Clinical Head, Pediatric Rheumatology and Immunology Clinical Services, Department of Pediatrics and Child-Health, Faculty of Medicine and Health Sciences Stellenbosch University, Cape Town, South Africa

N A Yunis, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa

Paediatric Rheumatologist Department of Pediatrics and Child Health, Faculty of Medicine and Health Sciences Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.

R H Glashoff, Department of Pathology, National Health Laboratory Service and Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

Principal Scientist, Immunology Unit, Division of Medical Microbiology, Department of Pathology, National Health Laboratory Service and Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

H Rabie, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa

Professor and Clinical Unit Head, Paediatric Infectious Diseases Unit, Department of Pediatrics and Child Health, Faculty of Medicine and Health Sciences Stellenbosch University and Tygerberg Academic Hospital, Cape Town, South Africa.

M M Van der Zalm, Desmond Tutu TB Centre, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa

Associate Professor and Paediatric Specialist, Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

A Lachman, Child and Adolescent Psychiatric Inpatient Unit, Faculty of Medicine and Health Sciences and Tygerberg Academic Hospital, Stellenbosch University, Cape Town, South Africa

Head of Clinical Unit, Child and Adolescent Psychiatry, Tygerberg Hospital, Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.

How to Cite

Long-term mental health and wellness of South African children treated for multisystem inflammatory syndrome in children: An observational study. (2025). South African Journal of Child Health, 19(3), e3162. https://doi.org/10.7196/

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