Factors associated with advanced HIV in the Tshwane District drainage area: A protocol for a cross-sectional analytical study

Main Article Content

S Nair
K M Tshabalala
F Abdullah

Abstract




Background. HIV continues to be a global pandemic. Despite significant achievements in reaching the global 95-95-95 targets, advanced HIV disease (AHD) continues to contribute to substantial morbidity and mortality, with 600 000 deaths worldwide in 2022 including 51 000 in South Africa (SA). The patient demographic has shifted from antiretroviral therapy (ART)-naïve individuals to those facing treatment interruptions or non-adherence.


Objective. To explore the factors associated with AHD in patients within the Tshwane District drainage area, SA, where high treatment coverage has not fully curbed mortality rates.


Method. This cross-sectional analytical study employs both quantitative and qualitative methods, utilising structured questionnaires and blood samples to assess ART levels, specifically dolutegravir. A minimum of 10 participants will undergo semi-structured interviews to explore their treatment experiences. Quantitative data will be analysed using descriptive and inferential statistics, while qualitative data will be examined through thematic analysis.


Conclusion. This research aims to enhance the understanding of AHD-related factors to inform effective interventions and policies for HIV care.




Article Details

How to Cite
Factors associated with advanced HIV in the Tshwane District drainage area: A protocol for a cross-sectional analytical study. (2024). Southern African Journal of Public Health, 7(3), e2564. https://doi.org/10.7196/SHS.2024.v7.i3.2564
Section
Original Articles
Author Biographies

K M Tshabalala , Department of Public Health Medicine, Steve Biko Academic Hospital, University of Pretoria, South Africa

Rank - Public Health Medicine Specialist.

Department - Department of Public Health Medicine, Steve Biko Academic Hospital 

University - School of Health Systems and Public Health, University of Pretoria 

 

F Abdullah, Department of Public Health Medicine, Steve Biko Academic Hospital, University of Pretoria, South Africa; Office of AIDS and TB Research, South African Medical Research Council, Pretoria, South Africa; Division of Infectious Diseases, Department of Internal Medicine, Faculty of Health Sciences, University of Pretoria, South Africa

Rank - Director at the Office of AIDS and TB Research

Department - Department of Public Health Medicine, Steve Biko Academic Hospital 

University - School of Health Systems and Public Health, University of Pretoria

How to Cite

Factors associated with advanced HIV in the Tshwane District drainage area: A protocol for a cross-sectional analytical study. (2024). Southern African Journal of Public Health, 7(3), e2564. https://doi.org/10.7196/SHS.2024.v7.i3.2564

References

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