The South African Prostate Cancer Screening Guidelines


  • J John Division of Urology, Department of Surgery, Faculty of Medicine and Health Sciences, Walter Sisulu University, East London, South Africa; Division of Urology, Department of Surgery, Faculty of Health Sciences, University of Cape Town, South Africa
  • A Adam Division of Urology, Department of Surgery, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
  • L Kaestner Division of Urology, Department of Surgery, Faculty of Health Sciences, University of Cape Town, South Africa
  • P Spies Division of Urology, Department of Surgery, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa
  • S Mutambirwa Division of Urology, Department of Surgery, School of Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa
  • J Lazarus Division of Urology, Department of Surgery, Faculty of Health Sciences, University of Cape Town, South Africa



prostrate, guidelines


Prostate cancer (PCa) is the most widespread solid organ malignancy in males and ranks as the fifth leading cause of death globally. Identifying and treating men with clinically significant disease while avoiding the over-diagnosis and over-treatment of indolent disease remains a significant challenge. Several professional associations have developed guidelines on screening and early diagnosis of asymptomatic men with prostate-specific antigen testing. With recent updates from several large randomised prospective trials, the South African Urological Association and the Prostate Cancer Foundation of South Africa have developed these evidence-based recommendations to guide clinicians on PCa screening and early diagnosis for South African men.


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How to Cite

John J, Adam A, Kaestner L, Spies P, Mutambirwa S, Lazarus J. The South African Prostate Cancer Screening Guidelines. S Afr Med J [Internet]. 2024 May 9 [cited 2024 May 19];114(5):e2194. Available from:

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