Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa

Authors

  • I Rukasha Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa; Department of Medical Microbiology, National Health Laboratory Services, Polokwane, South Africa
  • S T S Pheeha Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa; Department of Haematology, National Health Laboratory Services, Polokwane, South Africa
  • M R Lekalakala Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa; Department of Medical Microbiology, National Health Laboratory Services, Polokwane, South Africa
  • P Malope Division of Medical Microbiology, Department of Pathology, Faculty of Health Sciences, University of Limpopo, South Africa

DOI:

https://doi.org/10.7196/SAMJ.2024.v114i3.702

Keywords:

COVID-19, Seroprevalence, pregnant women, Immunoglobulin

Abstract

Background. COVID-19 has been a major public health concern globally, leading to a higher mortality rate, especially among immunosuppressed individuals, who include pregnant women, people with HIV and people living with other comorbidities. Pregnant women are considered to be a special population group owing to their specific susceptibility to some infectious diseases.

Objective. To determine the seroprevalence of anti-SARS-CoV-2 antibodies among pregnant women attending an antenatal clinic. Method. This was a descriptive cross-sectional study that tested blood samples from pregnant women who attended the antenatal clinic from March to July 2022 using the Orient Gene Biotech lateral flow immune-chromatographic assay according to manufacturer instructions. The assay detects IgM and IgG antibodies against SARS-CoV-2.

Results. A total of 2 649 blood samples were tested; 2 039 (77.0%) samples tested positive for IgG, 7 (0.3%) tested positive for IgM, and 100 (3.7%) tested positive for both IgG and IgM. The study found a seroprevalence of 80.7% of IgG.

Conclusion. The study findings showed evidence of acute COVID-19 infection in our patient population despite the consensus that COVID-19 infection is dissipating.

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Published

2024-03-18

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Section

Research

How to Cite

1.
Rukasha I, Pheeha STS, Lekalakala MR, Malope P. Determination of anti-COVID-19 IgG and IgM seroprevalence among pregnant women at Pietersburg Hospital, Limpopo Province, South Africa. S Afr Med J [Internet]. 2024 Mar. 18 [cited 2024 Apr. 21];114(3):e702. Available from: https://samajournals.co.za/index.php/samj/article/view/702

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