Takayasu’s arteritis in pregnancy: A case report
Main Article Content
Abstract
Takayasu’s arteritis (TA) is a large-vessel vasculitis predominantly affecting the aorta and its branches. It most commonly affects women in the second and third decades of life. Although analyses of case series and case studies have been done, no definitive consensus on optimal management has been reached. We describe the clinical course of an 18-year-old woman at 31weeks and 5 days’ gestation with active TA Type III (with multiple areas of stenosis, including both renal arteries, and areas of aneurysmal dilatation), uncontrolled hypertension and uveitis, with a favourable maternal and fetal outcome through a multidisciplinary approach.
Article Details
Issue
Section
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The SAJOG is published under an Attribution-Non Commercial International Creative Commons Attribution (CC-BY-NC 4.0) License. Under this license, authors agree to make articles available to users, without permission or fees, for any lawful, non-commercial purpose. Users may read, copy, or re-use published content as long as the author and original place of publication are properly cited.
Exceptions to this license model is allowed for UKRI and research funded by organisations requiring that research be published open-access without embargo, under a CC-BY licence. As per the journals archiving policy, authors are permitted to self-archive the author-accepted manuscript (AAM) in a repository.
How to Cite
References
1. JohnstonSL,LockRJ,GompelsMM.Takayasuarteritis:Areview.JClinPathol2002;55(7):481-486.
https://doi.org/10.1136/jcp.55.7.481
2. Hauenstein E, Frank H, Bauer JS, Schneider KTM, Fischer T. Takayasu’s arteritis in pregnancy: Review of literature and discussion. J Perinat Med 2010;38(1):55-62. https://doi.org/10.1515/ jpm.2009.120
3. Comarmond C, Saadoun D, Nizard J, Cacoub P. Pregnancy issues in Takayasu arteritis. Semin
Arthritis Rheum 2020;50(5):911-914. https://doi.org/10.1016/j.semarthrit.2020.08.001
4. Kraemer B, Abele H, Hahn M, et al. A successful pregnancy in a patient with Takayasu’s arteritis.
Hypertens Pregnancy 2008;27(3):247-252. https://doi.org/10.1080/10641950801955741
5. Assad APL, Da Silva TF, Bonfa E, Pereira RMR. Maternal and neonatal outcomes in 89 patients with Takayasu arteritis (TA): Comparison before and after the TA diagnosis. J Rheumatol
2015;42(10):1861-1864. https://doi.org/10.3899/jrheum.150030
6. Serra R, Butrico L, Fugetto F, et al. Updates in pathophysiology, diagnosis and management of
Takayasu arteritis. Ann Vasc Surg 2016;35:210-225. https://doi.org/10.1016/j.avsg.2016.02.011
7. Espinoza JL, Ai S, Matsumura I. New insights on the pathogenesis of Takayasu arteritis: Revisiting
the microbial theory. Pathogens 2018;7(3):73. https://doi.org/10.3390/pathogens7030073
8. GotwayMB,AraozPA,MacedoTA,etal.ImagingfindingsinTakayasu’sarteritis.AmJRoentgenol
2005;184(6):1945-1950. https://doi.org/10.2214/ajr.184.6.01841945
9. Li Cavoli G, Mulè G, Vallone MG, Caputo F. Takayasu’s disease effects on the kidneys: Current
perspectives. Int J Nephrol Renov Dis 2018;11:225-233. https://doi.org/10.2147/IJNRD.S146355 10. Grayson PC, Alehashemi S, Bagheri AA, et al. 18 F-fluorodeoxyglucose-positron emission tomography as an imaging biomarker in a prospective, longitudinal cohort of patients with large
vessel vasculitis. Arthritis Rheumatol 2018;70(3):439-449. https://doi.org/10.1002/art.40379
11. Itani R, Elmallahi N, Ramadan MAA, Al Ibrahim A. Pregnancy with Takayasu’s arteritis: A case
report and literature review. Cureus 2018;10(9):e3370. https://doi.org/10.7759/cureus.3370
12. Águeda AF, Monti S, Luqmani RA, et al. Management of Takayasu arteritis: A systematic literature review informing the 2018 update of the EULAR recommendation for the management of large
vessel vasculitis. RMD Open 2019;5(2):e001020. https://doi.org/10.1136/rmdopen-2019-001020 13. Ross C, D’Souza R, Pagnoux C. Pregnancy outcomes in systemic vasculitides. Curr Rheumatol Rep
2020;22(10):63. https://doi.org/10.1007/s11926-020-00940-5
14. Natekar A, Pupco A, Bozzo P, Koren G. Safety of azathioprine use during pregnancy. Can Fam
Physician 2011;57(12):1401-1402.
15. Soma-Pillay P, Adeyemo A, Suleman FE. Takayasu arteritis in pregnancy: Case report. Cardiovasc
J Afr 2015;26(1):e14-e16. https://doi.org/10.5830/CVJA-2015-003