Challenges in setting up the antiretroviral paediatric registry in South Africa: Lessons learned from Free State Province clinics

Authors

  • B R Omotoso Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa https://orcid.org/0000-0002-7989-6959
  • R Baleni Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa
  • M Dheda Pharmacovigilance Centre for Public Health, National Department of Health, Dr AB Xuma Building, Pretoria, South Africa
  • T Mofokeng Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa

DOI:

https://doi.org/10.7196/SAMJ.2024.v114i7.2115

Keywords:

HIV, pediatric, adverse drug reactions

Abstract

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Author Biographies

  • R Baleni, Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa

    Clinical Project Coordinator/Manager

  • T Mofokeng, Department of Internal Medicine, Faculty of Health Sciences, University of the Free State, Bloemfontein, South Africa

    Professor of Internal Medicine, Principal Investigator 

References

Archary M, Van Zyl R, Sipambo N, Sorour G. Opinion paper: Optimised paediatric antiretroviral treatment to achieve the 95-95-95 goals. South Afr J HIV Med 2021;22(1):a1278. https://doi. org/10.4102/ sajhivmed. v22i1.1278

UNAIDS. AIDS and the Sustainable Development Goals. Geneva: UNAIDS, 2024. https://www. unaids.org/en/AIDS_SDGs#:~:text=A%20core%20principle%20of%20the,health%20and%20 vulnerability%2C%20being%20addressed (accessed 16 June /2024).

Van Liere GA, Lilian R, Dunlop J, et al. 2021. High rate of loss to follow-up and virological non-suppression in HIV-infected children on antiretroviral therapy highlights the need to improve quality of care in South Africa. Epidemiol Infect 2021;149:e88. https://doi.org/10.1017/ S0950268821000637

World Data Atlas 2021. https://www.unaids.org/sites/default/files/media_asset/2020_aids-data-book_ en.pdf (accessed 31 March /2024).

Joint United Nations Programme on Hiv/Aids (UNAIDS). UNAIDS Data 2023. https://www.unaids. org/en/resources/documents/2024/unaids-data (accessed 30 March 2024).

Ngoyi K, Hlabyago K, Ogunbanjo G, Steyn C, Bongongo, T. Prevalent clinical assessments of HIV positive infants in a South African district hospital. Open Public Health J 2024;17(1):E18749445278115. https://doi.org/10.2174/0118749445278115231228054735

Escosa-García L, Sainz T. HIV and ART in children. Front Pediatr 2022;10:1074684. https://doi. org/10.3389/fped.2022.1074684

Malinga S, Khan A, Archary M. Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal. South Afr J HIV Med 2023; 24(1):1458.

Amuge P, Lugemwa A. Wynne B, et al. Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomised ODYSSEY trial. The Lancet HIV, 2022;9(9):e638-e648. https://doi.org/10.1016/S2352- 3018(22)00163-1

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Published

2024-07-01

Issue

Section

Editorials

How to Cite

1.
Omotoso BR, Baleni R, Dheda M, Mofokeng T. Challenges in setting up the antiretroviral paediatric registry in South Africa: Lessons learned from Free State Province clinics. S Afr Med J [Internet]. 2024 Jul. 1 [cited 2025 Apr. 22];114(7):e2115. Available from: https://samajournals.co.za/index.php/samj/article/view/2115