Pregnant patients with severe headaches – don’t forget brain tumours!

Authors

  • T Hassim Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa
  • D Hall Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa https://orcid.org/0000-0002-2344-3969
  • P Mjuleka Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa

DOI:

https://doi.org/10.7196/

Keywords:

Pregnancy, Meningioma, headaches, blindness, seizures

Abstract

Although sometimes innocuous, headaches in pregnancy may be associated with serious, even life-threatening conditions, with diagnosis delayed due to nonspecific findings associated with normal pregnancy. Meningiomas are the most common primary tumours, have a strong female predisposition and are mostly benign. There is a paucity of information on the diagnosis and management of meningiomas during and after pregnancy. In this article, we describe two cases of meningioma with differing management, seen within a period of 6 months. In case one, iatrogenic preterm delivery of the baby at 33 weeks’ gestation was executed to facilitate vision-saving neurosurgery. In our second case, delivery was at early term, with time allowed for postpartum re-evaluation before definitive neurosurgery.

Author Biographies

  • T Hassim, Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa

    Fellow Maternal-Fetal Medicine 

    Department Obstetrics & Gynaecology

    Tygerberg Hospital

  • D Hall, Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa

    Professor and Principal Specialist Maternal and Fetal Medicine Department Obstetrics and Gynaecology Tygerberg Hospital

  • P Mjuleka, Department of Obstetrics and Gynaecology, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa

    Senior registrar Department Obstetrics and Gynaecology Tygerberg Hospital

References

1. Lusis EA, Scheithauer BW, Yachnis AT, et al. Meningiomas in pregnancy: A clinicopathologic study of 17 cases. Neurosurgery 2012;71(5):951-961. https://doi.org/10.1227/NEU.0b013e31826adf65

2. Ogasawara C, Philbrick BD, Adamson DC. Meningioma: A review of epidemiology, pathology, diagnosis, treatment, and future directions. Biomedicines 2021;9(3):319. https://doi.org/10.3390/ biomedicines9030319

3. Mallari RJ, Thakur JD, Griffiths C, et al. Tuberculum sellae meningiomas in pregnancy: 3 cases treated in the second trimester and literature review. World Neurosurg 2020;143:268-275. https://doi. org/10.1016/j.wneu.2020.07.198

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Published

2025-05-02

Issue

Section

In Practice

How to Cite

1.
Hassim T, Hall D, Mjuleka P. Pregnant patients with severe headaches – don’t forget brain tumours!. S Afr Med J [Internet]. 2025 May 2 [cited 2025 May 13];115(4):e2699. Available from: https://samajournals.co.za/index.php/samj/article/view/2699