Ivermectin drug induced liver injury

Authors

  • Mark Sonderup Division of Hepatology and Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital
  • Washington Mudini Department of Anatomical Pathology and the National Health Laboratory System, D7, University of Cape Town and Groote Schuur Hospital
  • Wendy Spearman Division of Hepatology and Department of Medicine, Faculty of Health Sciences, University of Cape Town and Groote Schuur Hospital

DOI:

https://doi.org/10.7196/SAMJ.2023.v113i6.624

Keywords:

Ivermectin, hepatotoxicity

Abstract

Ivermectin remains a popular, albeit unproven, therapy used in both the prevention and treatment of COVID-19. We discuss a patient who developed jaundice and a liver injury 3 weeks after initiating ivermectin for COVID prevention.  Liver histology demonstrated a pattern of injury that was both portal and lobular, with a bile ductulitis as well with marked cholesasis. She was managed with low dose corticosteroids, later tapered and withdrawn. She remains well a year after presenting.

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Published

2023-06-05

Issue

Section

In Practice

Categories

How to Cite

1.
Sonderup M, Mudini W, Spearman W. Ivermectin drug induced liver injury. S Afr Med J [Internet]. 2023 Jun. 5 [cited 2024 May 19];113(6):24-5. Available from: https://samajournals.co.za/index.php/samj/article/view/624

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