Issues in Medicine

Transcatheter vascular plugs for the treatment of massive haemoptysis from Rasmussen aneurysms

Authors

  • J A Shaw DSI-NRF Centre of Excellence for Biomedical Tuberculosis Research; South African Medical Research Council Centre for Tuberculosis Research; Biomedical Research Institute, Division of Molecular Biology and Human Genetics, and Division of Pulmonology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa
  • T J John Division of Cardiology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa
  • C F N Koegelenberg Division of Pulmonology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa
  • M da Silva Division of Radiodiagnosis, Department of Medical Imaging and Clinical Oncology, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa
  • B W Allwood Division of Pulmonology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa
  • H Weich Division of Cardiology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa

DOI:

https://doi.org/10.7196/SAMJ.2022.v113i2.16758

Keywords:

Lung infection, TB

Abstract

Rasmussen aneurysms are abnormalities of the pulmonary arterial system caused by tuberculosis (TB). They are associated with a high
mortality rate when they cause life-threatening haemoptysis. High TB-prevalence regions have a large burden of TB-related haemoptysis
but often limited resources. This series of 25 patients who presented with life-threatening haemoptysis from current and/or previous TB
were found to have abnormal pulmonary arteries on computed tomography pulmonary angiogram (CTPA), which were judged to be
likely contributors to their bleeding, either in isolation or with concomitant abnormal bronchial or systemic vasculature. These patients
underwent transcatheter placement of Amplatzer vascular plugs in the feeder pulmonary artery. Bronchial and systemic lesions were
addressed separately as needed. Immediate technical success was achieved in all patients, but four of them experienced intraoperative
haemoptysis related to dislodgement of the occluding platelet plug by the high-pressure automatic injector and wire. At 48 hours after the
procedure, 18 (72%) remained haemoptysis-free. Six of these experienced recurrence within 1 year of their procedure. Pulmonary artery
placement of an Amplatzer vascular plug is a feasible option for treating bleeding Rasmussen aneurysms, but should be part of a combined
approach to addressing suspected culprit vascular lesions in all intrathoracic vascular systems.

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Published

2023-02-01

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Section

In Practice

How to Cite

1.
Shaw JA, John TJ, Koegelenberg CFN, da Silva M, Allwood BW, Weich H. Issues in Medicine: Transcatheter vascular plugs for the treatment of massive haemoptysis from Rasmussen aneurysms. S Afr Med J [Internet]. 2023 Feb. 1 [cited 2024 Dec. 9];113(2):65-8. Available from: https://samajournals.co.za/index.php/samj/article/view/731

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