‘Forgotten’ goitre after total thyroidectomy
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Abstract
Background. ‘Forgotten’ goitre (FG) is a mediastinal portion of the thyroid found after total thyroidectomy. It is extremely rare.
Objectives. To report on 5 cases and review the literature.
Methods. We retrospectively reviewed all patients with retrosternal goitre at Mohammed V Military Teaching Hospital, Rabat, Morocco, from 1 January 2010 to 31 December 2020 and identified 5 patients who underwent surgery for forgotten mediastinal goitre during this period. Data on patient characteristics, time of the first thyroidectomy, imaging (chest radiograph, chest computed tomography (CT) scan and magnetic resonance imaging), surgical approach, pathological findings and postoperative complications were collected.
Results. Five patients (3 female and 2 male) with a mean age of 46.2 years (range 32 - 56 years) with FG had surgery. Two patients were asymptomatic and 3 patients had dyspnoea, 2 of whom also had dysphonia and 1 signs of hyperparathyroidism. No patient had a history of thyroid cancer. The average time between the first thyroidectomy and re-operation was 4.3 years. The diameter of the masses on CT scan was 7 - 12 cm. All the patients underwent sternotomy. Postoperative transitory left recurrent laryngeal nerve palsy occurred in 1 case. There were no postoperative deaths. Pathological examination of the mediastinal goitre confirmed multi-heteronodular thyroid hyperplasia in all cases.
Conclusion. FG is an extremely rare condition, which can be prevented with thorough preoperative imaging.
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References
1. Calò PG, Tatti A, Medas F, Petruzzo P, Pisano G, Nicolosi A. Forgotten goiter: Our experience and a review of the literature. Ann Ital Chir 2012;83(6):487-490.
2. Massard G, Wihlm JM, Jeung MY, et al. [Forgotten mediastinal goiter: Seven cases.] Ann Chir 1992;46(8):770-773.
3. AveniaN,SantopreteS,MonacelliM,etal.Theforgottengoiter:Casuisticcontribution and considerations for the choice of surgical approach. Cent Eur J Med 2013;8(4):415- 419. https://doi.org/10.2478/s11536-013-0183-4
4. Lucchini R, Santoprete S, Monacelli M, et al. Forgotten goiter: Our experience. Minerva Chir 2014;69(Suppl 1):19-22.
5. Fattovich G, Franceschini F, D’Atri C. Il gozzo ‘mediastinico’ dimenticato. Chir Triveneta 1994;34(1):10-14.
6. Sahbaz A, Aksakal N, Ozcinar B, Onuray F, Caglayan K, Erbil Y. The ‘forgotten’ goiter after total thyroidectomy. Int J Surg Case Rep 2013;4(3):269-271. https://doi. org/10.1016/j.ijscr.2012.11.014
7. Oueriachi FE, El Hammoumi MM, Arsalane A, Slaoui O, Diouri H, Kabiri el H. Primary mediastinal goiters. Springerplus 2014;3:503. https://doi.org/10.1186/2193- 1801-3-503
8. Patel KM, Parsons CC. Forgotten goiter: Diagnosis and management. A case report and literature review. Int J Surg Case Rep 2016;27:192-194. https://doi.org/10.1016/j. ijscr.2016.08.036
9. Faroq Abdulrahman SM, Teksöz S, Ferahman S, Demiryas S, Bükey Y, Özyiğin A. Missed thyroid gland after total thyroidectomy. Turk J Surg 2018;34(2):137-139. https://doi.org/10.5152/turkjsurg.2017.3206
10. Sackett WR, Reeve TS, Barraclough B, Delbridge L. Thyrothymic thyroid rests: Incidence and relationship to the thyroid gland. J Am Coll Surg 2002;195(5):635- 640. https://doi.org/10.1016/s1072-7515(02)01319-4
11. Ismail AM, AlFehaid MS, Binyousef H. Forgotten retrosternal goiter. Saudi Surg J 2019;7(2):79-81. https://doi.org/10.4103/ssj.ssj_39_18
12. Courvoisier T, Donatini G, de Calan L, Miraillié E. Forgotten goiter (FG): Lesson learned from a multicentric experience. Eur J Surg Oncol 2015;41(10):S82-S83. https://doi.org/10.1016/j.ejso.2015.08.088
13. El Hammoumi M, El Oueriachi F, Arsalane A, Kabiri el H. [Surgical management of retrosternal goiter: Experience of a Moroccan centre.] Acta Otorrinolaringol Esp 2014;65(3):177-182. https://doi.org/10.1016/j.otorri.2013.12.009
14. Grigoletto R, Toniato A, Piotto A, et al. [A case of forgotten giant goiter.] Minerva Chir 1997;52(7-8):943-948.
15. Khan FW, Muhammad A, Abbas M, Bin Mahmood SU, Fatima B, Fatimi SH. Delayed presentation of forgotten thyroid goiter – 25 years after thyroidectomy. J Coll Physicians Surg Pak 2016;26(10):858-860.
16. LeeJ,NamKH,LimCY,ChangHS,ChungWY,ParkCS.Forgottenmediastinalgoiter. Korean J Endocr Surg 2005;5(2):114-117. https://doi.org/10.16956/kjes.2005.5.2.114 17. Casadei R, Perenze B, Calculli L, Minni F, Conti A, Marrano D. [‘Forgotten’ goiter:
Clinical case and review of the literature.] Chir Ital 2002;54(6):855-860.
18. Kesici U, Koral Ö, Karyağar S, et al. Missed retrosternal ectopic thyroid tissue in a patient operated for multinodular goiter. Ulus Cerrahi Derg 2015;32(1):67-70. https://
doi.org/10.5152/UCD.2015.2916
19. Tsakiridis K, Visouli AN, Zarogoulidis P, et al. Resection of a giant bilateral retrovascular intrathoracic goiter causing severe upper airway obstruction, 2 years after subtotal thyroidectomy: A case report and review of the literature. J Thorac Dis 2012;4(Suppl 1):41-48. https://doi.org/10.3978/j.issn.2072-1439.2012.s004
20. PaczkowskaK,RollaM,ElbaumM,JędrzejukD,BolanowskiM,DaroszewskiJ.Large ‘forgotten goiter’ in the thoracic cavity – a case report. Endocr Abstr 2020;70:AEP978. https://doi.org/10.1530/endoabs.70.AEP978