3-Tesla cardiac magnetic resonance imaging in primary dilated cardiomyopathy
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Abstract
Background. Cardiac magnetic resonance imaging (CMR) is an excellent non-invasive imaging tool in the assessment of patients with dilated cardiomyopathy (DCM). Few studies have analysed the findings in primary (idiopathic) DCM.
Objectives. To study the CMR features in primary DCM.
Methods. We conducted a descriptive observational study on 20 adult patients with suspected or confirmed primary DCM. Each patient underwent a dedicated 3-Tesla CMR scan, and the findings were evaluated.
Results. Seventeen patients had systolic dysfunction with a reduced ejection fraction and elevated end-diastolic volume, 19 patients had contractile dysfunction in the form of global left ventricular hypokinesia, 13 patients showed no abnormal delayed contrast enhancement with gadolinium administration, and 7 patients showed abnormal late gadolinium enhancement patterns.
Conclusion. In patients with primary DCM, CMR is a powerful diagnostic tool that can definitively establish the diagnosis, assess the severity of the disease, predict the risk of future adverse cardiovascular outcomes, check for complications, and assist in future follow-ups.
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Fan ZX, Wang CB, Fang LB, et al. Risk factors and a Bayesian network model to predict ischemic stroke in patients with dilated cardiomyopathy. Front Neurosci 2022;16:1043922. https://doi.org/10.3389/fnins.2022.1043922
Walker BR, Colledge NR, Ralston SH, Penman I. Davidson’s Principles and Practice of Medicine E-Book. 22nd ed. Elsevier Health Sciences, December 2013.
Hershberger RE, Jordan E. Dilated cardiomyopathy overview. 27 July 2007 (updated 7 April 2022). In: Adam MP, Feldman J, Mirzaa GM, et al., eds. GeneReviews. Seattle: University of Washington, 1993-2024. https://www.ncbi.nlm.nih.gov/books/ NBK1309/ (last accessed 16 February 2024).
Mahmaljy H, Yelamanchili VS, Singhal M. Dilated cardiomyopathy (updated 7 April 2023). In: StatPearls. Treasure Island, Fla.: StatPearls Publishing, 2024. https://www. ncbi.nlm.nih.gov/books/NBK441911/ (last accessed 16 February 2024).
Seidman JG, Seidman C. The genetic basis for cardiomyopathy: From mutation identification to mechanistic paradigms. Cell 2001;104(4):557-567. https://doi. org/10.1016/S0092-8674(01)00242-2
Schultheiss HP, Fairweather D, Caforio ALP, et al. Dilated cardiomyopathy. Nat Rev Dis Primers 2019;5(1):32. https://doi.org/10.1038/s41572-019-0084-1
Divakaran S, Singh A, Collins B, et al. Role of imaging in evaluating infiltrative heart disease. Curr Treat Options Cardiovasc Med 2017;19(1):3. https://doi.org/10.1007/ s11936-017-0500-3
Ordovas KG, Higgins CB. Delayed contrast enhancement on MR images of myocardium: Past, present, future. Radiology 2011;261(2):358-374. https://doi. org/10.1148/radiol.11091882
BelloniE,deCobelliF,EspositoA,etal.MRIofcardiomyopathy.AJRAmJRoentgenol 2008;191(6):1702-1710. https://doi.org/10.2214/AJR.07.3997
François CJ, Schiebler ML, Reeder SB. Cardiac MRI evaluation of nonischemic cardiomyopathies. J Magn Reson Imaging 2010;31(3):518-530. https://doi. org/10.1002/jmri.22030
Assomull RG, Prasad SK, Lyne J, et al. Cardiovascular magnetic resonance, fibrosis, and prognosis in dilated cardiomyopathy. J Am Coll Cardiol 2006;48(10):1977-1985. https://doi.org/10.1016/j.jacc.2006.07.049
O’Donnell DH, Abbara S, Chaithiraphan V, et al. Cardiac MR imaging of nonischemic cardiomyopathies: Imaging protocols and spectra of appearances. Radiology 2012;262(2):403-422. https://doi.org/10.1148/radiol.11100284
Rihal CS, Nishimura RA, Hatle LK, Bailey KR, Tajik AJ. Systolic and diastolic dysfunction in patients with clinical diagnosis of dilated cardiomyopathy: Relation to symptoms and prognosis. Circulation 1994;90(6):2772-2779. https://doi. org/10.1161/01.CIR.90.6.2772
McCrohon JA, Moon JCC, Prasad SK, at al. Differentiation of heart failure related to dilated cardiomyopathy and coronary artery disease using gadolinium-enhanced cardiovascular magnetic resonance. Circulation 2003;108(1):54-59. https://doi. org/10.1161/01.CIR.0000078641.19365.4C
Tigen K, Karaahmet T, Kirma C, et al. Diffuse late gadolinium enhancement by cardiovascular magnetic resonance predicts significant intraventricular systolic dyssynchrony in patients with non-ischemic dilated cardiomyopathy. J Am Soc Echocardiogr 2010;23(4):416-422. https://doi.org/10.1016/j.echo.2009.12.022